吳世忠 副教授

Shyh-Jong Wu

Shyh-Jong Wu, Associate Professor

  • 研究室:濟世大樓CS607室
  • 實驗室:濟世大樓CS601室
  • 單位電話:(07)312-1101 ext.2354 or 2148
  • 電子信箱:sjwu@kmu.edu.tw

學歷

  • 台灣大學生理學研究所博士
  • 高雄醫學院醫學技術學系學士

經歷

  • 加拿大蒙特婁大學博士後研究(2006-2008)
  • 高雄醫學大學醫學檢驗生物技術學系助理教授 (2004~)
  • 中央研究院動物所博士後研究 (~2004)

研究興趣

神經退化疾病的致病機轉與預防機制;心血管疾病的致病機轉;高血脂對糖尿病的影響機制;基因多型性(SNP)在慢性疾病中的角色。

論文著作 (*corresponding author)

  1. Chen WH, Chu KC, Wu SJ, Wu JC, Shui HA, Wu ML*. Early metabolic inhibition-induced intracellular sodium and calcium increase in rat cerebellar granule cells. J. Physiol. (Lond.) 1999 Feb 15;515 ( Pt 1):133-46. (SCI)
  2. Wu SJ, Chiang FT, Jiang JR, Hsu KL, Chern TH, and Tseng YZ*. The G–217A variant of the angiotensinogen gene affects basal transcription and is associated with hypertension in a Taiwanese population. J Hypertens. 2003 Nov;21(11):2061-2067. (SCI)
  3. Wu SJ, Chiang FT, Chen WJ, Liu PH, Hsu KL, Hwang JJ, Lai LP, Lin JL, Tseng CD, Tseng YZ*.Three single-nucleotide polymorphisms of the angiotensinogen gene and susceptibility to hypertension: single locus genotype vs. haplotype analysis. Physiol Genomics. 2004,17(2):79-86. (SCI)
  4. Liu F, Wei CC, Wu SJ, Chenier I, Zhang SL, Filep JG, Ingelfinger JR, Chan JS*. Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension. Kidney Int. 2009 Jan;75(2):156-66. (SCI)
  5. Lau GJ, Godin N, Maachi H, Lo CS, Wu SJ, Zhu JX, Brezniceanu ML, Chénier I, Fragasso-MarquisJ, Lattouf JB, Ethier J, Filep JG, Ingelfinger JR, Nair V, Kretzler M, Cohen CD, Zhang SL, Chan JS. Bcl-2 modifying factor induces renal proximal tubular cell apoptosis in diabetic mice. Diabetes. 2012 Feb;61(2):474-84. (SCI)
  6. Soulez M, Pilon EA, Dieudé M, Cardinal H, Brassard N, Qi S, Wu SJ, Durocher Y, Madore F, Perreault C, Hébert MJ*. The Perlecan Fragment LG3 Is a Novel Regulator of Obliterative Remodeling Associated With Allograft Vascular Rejection. Circ Res. 2012 Jan 6;110(1):94-104. (SCI)

INTERNATIONAL CONFERENCES

  1. “Molecular variants of angiotensinogen gene promoter affect in-vitro basal transcription” Wu SJ, Chiang FT, Jiang JR, Hsu KL, Chern TH, Tseng YZ. The 24th Annual Scientific Meeting of Japanese Society of Hypertension 2001. (Held at OSAKA, ). (Oral presentation of young investigators)
  2. “BCL-2 MODIFYING FACTOR IS DIFFERENTIALLY UPREGULATED AND INDUCES APOPTOSIS IN RENAL PROXIMAL TUBULAR CELLS OF DB/DB MICE” Wu SJ, Liu F, Wei CC, Chenier I, Zhang SL, Filep JG, Ingelfinger JR, Chan JS*. The Canadian Society of Nephrology Annual Meeting at the London Convention Centre, London, Ontario , May 30th to June 1st, 2008. (Oral presentation)
  3. “The initiatory source of local Ang II to induce vascular remodeling comes from the apoptotic endothelial cells” Wu SJ*, Tsai ML, Chiang FT, Hébert MJ 21st European Meeting on Hypertension and Cardiovascular Prevention at Milano, Italy, Jun 17th-20th, 2011 (Poster)
  4. “Functional Regulation of Alu Element of ACE Gene in Neuron Cell” Wu SJ, Tsai ML, Chen CH, Yang YH*. The Fifth Congress of the Asian Society Against Dementia at Hongkong, Nov 5th-7th, 2011. (Oral presentation)
  5. “Functional examination of HU-YI-NENG, diet supplement, in its anti-oxidant effects” Wu SJ*, Chen CH, Tsei ML, Hseih TJ, Yang YH. Alzheimer’s Association International Conference (AAIC), Vancouver, British Columbia, Canada, Jul 14th-19th, 2012. (Poster)

產學合作計畫

  1. 『祥和護憶能膠囊對神經細胞保護的效用評估』,執行期間100.05.15~100.9.31;
  2. 『祥和星月寧膠囊對神經細胞血清素分泌的調節作用』,執行期間101.02.01~101.9.31。

 

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